CEREBRO

Among the non-invasive neuroimaging strategies, Electroencephalography (EEG) from scalp potentials is one of the primary. In EEG the neuroninduced electric potential is measured by using electrodes on the patient’s scalp. The skull however, highly resistive, shields EEG recordings limiting the spatial resolution. The standard way to avoid skull shielding effects is to invasively implant EEG electrodes under the skull (ECoG) or in the brain cortex (StereoEEG), in both cases after trepanning the patient’s skull. Scalp EEGs are noninvasive but lack spatial imaging accuracy. ECoG and StereoEEG are highly accurate but require skull trepanation and they image only a limited part of the brain. There is the need for increasing the resolution of scalp EEG providing the same level of accuracy of invasive EEGs.

This will be the grand challenge which CEREBRO will achieve by conceiving the first ever existing EEG contrast medium, able to provide imaging of the entire brain and in a non-invasive way.

CEREBRO is a new project selected within the highly selective EIC pathfinder open (56 projects selected for 868 proposals submitted). The calls funds projects that release highly innovative research towards game-changing technologies. The CEREBRO project has started in October 2022 for 48 months. IMT is WP leader.